- Mike Henry - Cleveland Brown, Rallo Tubbs
- Sanaa Lathan - Donna Tubbs-Brown
- Jason Sudeikis - Holt Richter, Terry Kimple i Kenny West
- Will Forte - Cleveland Brown Jr.
- Kevin Michael Richardson - Federline Jones, Lester Krinklesac
- Reagan Gomez-Preston - Roberta Tubbs
- Seth Green - Chris Powell
- Alex Borstein - Tricia Takanawa, Lois Griffin, Barbara
- Arianna Huffington - Arianna Huffington
– Jamie Kennedy – Robert
- Corey Holcomb - Kenny Loggins
– David Lynch – Gus
- Gilbert Gottfried - Strażnik krypty
– Patrick Stewart – On sam